Products

Triflon 100

TRIFLON® 100

Solution for injections

 

Description

Transparent yellow solution.

Composition

1 ml of the drug contains:

active ingredients: enrofloxacin – 100 mg; trimethoprim – 50 mg;

excipient: water for injections.

Pharmacological properties

АТСvet: QJ01. Antibacterials for systemic use.

Enrofloxacin is a broad-spectrum antibiotic of the fluoroquinolones group, which demonstrates activity against gram-positive and gram-negative microorganisms (Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp., Pseudomonas aeruginosa, E. coli, Haemophilus spp., Salmonella spp., Klebsiella spp., Proteus spp., Pasteurella spp. etc.) as well as mycoplasma (Mycoplasma spp.) and chlamydia (Chlamydia spp.). Its mechanism of action id related to inhibition of bacterial DNA-gyrase, which results in violation of DNA replication in microorganisms.

Trimethoprim is a broad-spectrum antibacterial of the diaminopyrimidines group. It is effective against gram-positive and gram-negative microorganisms (E. сolі, Klebsiella spp., Salmonella spp., Pasteurella spp., Enterobacter spp., Proteus spp., Shigella spp., Staphylococcus spp., Streptococcus spp., Haemophilus spp., Chlamydia spp.) as well as toxoplasmata and coccidia. The mechanism of action of trimethoprim consists in inhibition of bacterial reductase of dihydrofolic acid.

Administration

Treatment of diseases of digestive tract, respiratory organs and urinary system as well as skin and soft tissues caused by enrofloxacin- and trimethoprim-sensitive microorganisms in cattle and swine.

Dosage

Cattle. Administer subcutaneously in a dose of 2.5 ml of the drug per 100 kg body weight once daily for 3-5 days. In salmonellosis and diseases of respiratory organs administer 5 ml of the drug per 100 kg body weight once daily for 5 days.

Swine. Administer intramuscularly in a dose of 0.25 ml of the drug per 10 kg body weight once daily for 3 days. In salmonellosis and infections of respiratory organs administer 0.5 ml of the drug per 10 kg body weight once daily for 5 days.

Contraindications

Hypersensitivity to enrofloxacin and trimethoprim. Do not administer to pregnant swine. Do not administer Triflon®100 in combination with tetracycline, chloramphenicol, theophylline and non-steroidal anti-inflammatory agents.

Precautions

Animal slaughter for meat is possible in 14 days following the last administration. Consumption of milk is possible in 7 days following the last administration. Meat and milk obtained before the mentioned term shall be utilized or fed to non-productive animals depending on the statement of veterinary physician.

Packaging

Glass vials of 100 ml sealed with rubber stoppers and aluminum caps in cardboard boxes.

Storage

Store in a dry, dark place out of the reach of children at 5-30°С.

Shelf life

3 years.