Products

Tilotrin

TILOTRIN®

Solution for injections 

 

Description 

Transparent yellow solution.

Composition 

1 ml of the drug contains:

active ingredient: tilosin ( as tilosin tatrate) – 50 mg;

excipients - propylene glycol, water for injections.

Pharmacological properties

АТС vet  QJ01. Antibacterials for systemic use. QJ01FA90. Tilosin.

Tilosin is a macrolide antibiotic, which inhibits bacterial synthesis of proteins by way of binding to ribosomal 50S subunits. The drug makes bacteriostatic effect upon gram-positive (Actinomyces spp., Bacillus antracis, Clostridium spp., Corynebacterium spp., Erysipelothrix rhusiopathiae, Streptococcus spp.) and gram-negative microorganisms (Actinobacillus spp., Bordetella bronchiseptica, Fusobacterium spp., Haemophilus spp., Moraxella spp., Pasteurella spp., Proteus mirabilis, Salmonella spp.) as well as mycoplasma (Mycoplasma gallisepticum, M. hyopneumoniae, M. synoviae, M. meleagridis, M. agalactiae, M. bovigenitalium).

After intramuscular administration the antibiotic is quickly distributed in organs and tissues and reaches its maximum concentrations in about 1 hour following administration. The therapeutic level of substances in tissues is maintained for over 20 hours. Tilosin is eliminated from the body primarily with urine and milk.

Administration

The drug is used to treat animals against the following diseases caused by tilosin-sensitive microorganisms:

-          cattle: pneumonia, mastitis, pneumoenteritis, secondary bacterial infections in viral diseases;

-          sheep, goat: bronchial pneumonia, infectious agalactia, secondary bacterial infections in viral diseases;

-          swine: enzootic pneumonia, atrophic rhinitis, arthritis, dysentery, secondary bacterial infections in viral diseases;

-          turkeys: diseases of respiratory organs.

Dosage 

Administer intramuscularly once daily in the following doses:

 

Animal species

Drug doses

(ml per 1 kg body weight)

Cattle

0.1

Sheep, goats

0.2-0.24

Swine

0,2

Turkeys

0.1-0.2

 

Treatment period: 3-5 days.

Contraindications

Do not administer to animals with hypersensitivity to tilosin. Do not administer to animals with kidney and liver disorders. Do not administer in combination with penicillins, cephalosporins and lincomycin. Do not administer to horses. Do not administer to animals in pregnancy as well as to animals of the first week of life.

Precautions

Consumption of milk is possible in 4 days and animal slaughter for meat is possible in 8 days following the last administration. Milk and meat obtained before the mentioned term shall be utilized or fed to non-productive animals depending on the statement of veterinary physician.

Packaging

Glass vials of 100 ml sealed with rubber stoppers and aluminum caps.

Storage

Store in original packaging out of the reach of children at 0-30°С.

 

Shelf life

2 years.

28 days after the initial sampling provided it is stored in original packaging at 0-30°С.